Audiovestibular Manifestations in Patients with Ankylosing Spondylitis – A Case Report and Review of the Literature
Ankylosing spondylitis (AS) is a chronic systemic inflammatory disease. The disease primarily affects the axial skeleton and its cause is unknown; it is known to affect up to 1% of the population. The onset is usually in the 30s and affects men three tiRead More
Education and preventive care
Evidence and rationale. Self-management education interventions in AS were tested in 5 controlled trials, with generally small but significant improvements in measures of disease activity and health status.Read More
Arthritis and Ankylosing Spondylitis
Ankylosing spondylitis is a type of arthritis that affects the spine. Ankylosing spondylitis symptoms include pain and stiffness from the neck down to the lower back. The spine's bones (vertebrae) may grow or fuse together, resulting in a rigid spine. TRead More
HLA-B27: What’s New?
The HLA-B27 molecule is one of the most fascinating in medicine. Its contribution to the aetiopathogenesis of SpA and other diseases, and its protective action in certain infections, continue to challenge our understanding of its immunobiology and physiRead More
Basics of Ankylosing Spondylitis
Almost all people with ankylosing spondylitis can expect to lead normal and productive lives. Despite the chronic nature of the illness, only a few people with ankylosing spondylitis will become severely disabled. The management of pain and the controlRead More
Ramifications of HLA-B27
Thirty years after its discovery, the association between HLA-B27 and ankylosing spondylitis remains the strongest known relationship between a major histocompatibility complex (MHC) antigen and a disease. EpidemioloRead More
Symptoms and Signs
The most frequent manifestation is back pain, but disease can begin in peripheral joints, especially in children and women, and rarely with acute iridocyclitis (iritis or anterior uveitis). Other early symptoms and signs are diminished chest expansion fRead More
Leaky Gut Syndromes: Breaking The Vicious Cycle
From the perspective of function, the contents of the gut lumen lie outside the body and contain a toxic/antigenic load from which the body needs to be protected. Protection is supplied by complex mechanisms which support one another: intestinal secretiRead More