Psoriatic Arthritis

What is Psoriatic Arthritis

Psoriasis is a scaly rash that occurs most frequently on the elbows, knees and scalp, but can cover much of the body. It is a chronic, inflammatory disease of the skin, scalp, nails anpsoriatic arthritisd joints, often leading to psoriatic arthritis. Psoriasis is also considered one of the ankylosing spondylitis related diseases, as it belongs to the spondyloarthritis family. Normally, skin cells mature and shed from the body’s surface every 28 to 30 days, but in psoriasis, this process is much faster, causing cells to build up and form thick, scaly patches.

Up to 30% of people with psoriasis also develop psoriatic arthritis. In most cases the psoriasis will precede the arthritis, sometimes by many years. When arthritis symptoms occur with psoriasis, it is called psoriatic arthritis (PsA). In these cases, the joints at the end of the fingers are most commonly affected causing inflammation and pain, but other joints like the wrists, knees and ankles can also become involved. This is usually accompanied by symptoms of the fingernails and toes, ranging from small pits in the nails to nearly complete destruction and crumbling as seen in reactive arthritis or fungal infections.

About 20% of people who develop PsA will eventually have spinal involvement, which is called psoriatic spondylitis. The inflammation in the spine can lead to complete fusion – as in ankylosing spondylitis – or skip areas where, for example, only the lower back and neck are involved. Those with spinal involvement are most likely to test positive for the HLA-B27 genetic marker.

The least common type of psoriatic arthritis is also the most severe. Called ‘psoriatic arthritis mutilans’, it occurs in about 5% with psoriatic arthritis. Arthritis mutilans is the most severe form of arthritis associated with psoriasis. This form of the disease results in widespread destruction of the joints. When this affects the hands, it can cause a phenomenon sometimes referred to as ‘telescoping fingers.’ Similar changes can occur in the feet.

Psoriatic Arthritis (PsA) symptoms

Joint & Tendon Symptoms

  • Arthritis and stiffness mainly occurs in the hands, feet, the spine, and wrists. These symptoms can be worse after periods of rest.
  • Involvement of an entire finger or toe, which then swells like a sausage, is known as dactylitis.
  • Inflammation in areas where ligaments or tendons join a bone, like plantar fasciitis or the pain experienced by the Achilles tendon, is called enthesitis.
  • Joint pain or swelling in and around the affected joints is common.

Skin & Nail Symptoms (Often precede joint issues)

  • Psoriasis Rashes: Scaly, red patches (scalp, elbows, knees).
  • Fungal infections of the nails cause changes such as tiny dents, discoloration, crumbling or separation from the nailbed.

Other Common Symptoms

  • Fatigue: Significant tiredness or lack of energy.
  • Uveitis results in redness of the eye, vision loss, and also pain, cloudy vision. If you don’t get a proper and prompt treatment for uveitis you may lose your vision.
  • Back Pain: Stiffness in the spine (spondylitis).

What Causes Psoriatic Arthritis

The exact cause of psoriatic arthritis is not known, but it is known that heredity plays a large role. Up to 40% of people with PsA have a close relative with the disease, and if an identical twin has it, there is a 75% chance that the other twin will have PsA as well.

Is There a Cure for Psoriatic Arthritis ?

Although there is currently no known cure, there are treatments and medications available to reduce symptoms and manage the pain and inflammation caused by PsA.

Disease Course / Prognosis

Disease course and prognosis varies from individual to individual and also depends which form the disease takes (see above). For example, someone who is HLA-B27 positive is more likely to have the disease progress to involve the spine.

Also, the severity of the rash does not mirror the severity of the arthritis, and the skin condition does not necessarily occur at the same time as the arthritis.

Lifestyle, Diet, and Self-Care

While diet alone cannot cure psoriatic arthritis, it plays a meaningful role in treating psoriatic arthritis and managing daily symptoms. Many people find that focusing on foods that help spondylitis, such as anti-inflammatory options, can reduce discomfort. Understanding the role of diet in managing spondylitis and psoriatic arthritis may help lower inflammation, support joint health, and improve overall well-being.

Antar Dhwani